ChAMP: 450k Chip Analysis Methylation Pipeline
نویسندگان
چکیده
منابع مشابه
ChAMP: 450k Chip Analysis Methylation Pipeline
UNLABELLED The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylat...
متن کاملChAMP: updated methylation analysis pipeline for Illumina BeadChips
Summary The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for high-throughput DNA methylation analysis, effectively doubling the coverage compared to the older 450 K array. Here we present a significantly updated and improved version of the Bioconductor package ChAMP, which can be used to analyze EPIC and 450k data. Many enhanced functionalities have been added, including ...
متن کاملErratum: A meta-analysis on age-associated changes in blood DNA methylation: results from an original analysis pipeline for Infinium 450k data
Aging is characterized by a profound remodeling of the epigenetic architecture in terms of DNA methylation patterns. To date the most effective tool to study genome wide DNA methylation changes is Infinium HumanMethylation450 BeadChip (Infinium 450k). Despite the wealth of tools for Infinium 450k analysis, the identification of the most biologically relevant DNA methylation changes is still cha...
متن کاملshinyMethyl: interactive visualization of Illumina 450K methylation arrays
Up to now, more than 10,000 methylation samples from the state-of-the-art 450K microarray have been made available through The Cancer Genome Atlas portal [1] and the Gene Expression Omnibus (GEO) [2]. Large-scale comparison studies, for instance between cancers or tissues, become possible epigenome-widely. These large studies often require a substantial amount of time spent on preprocessing the...
متن کاملpyMAP: a Python package for small and large scale analysis of Illumina 450k methylation platform
Summary: PyMAP is a native python module for analysis of 450k methylation platform and is freely available for public use. The package can be easily deployed to cloud platforms that support python scripting language for large-scale methylation studies. By implementing fast parsing functionality, this module can be used to analyze large scale methylation datasets. Additionally, command-line exec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt684